Category Archives: Transplants and Infusions

Andy's Story – The Lifesaving Potential of Sibling Cord Blood | ViaCord

Trevinos KidsMost families see cord blood banking as a valuable opportunity – a chance to preserve stem cells that, if one of their children falls ill in the future, might provide a lifesaving treatment option. Andres and Paulina Treviño are a startling exception: when they banked their daughter Sofia’s cord blood with Viacord, they already planned to use her stem cells to treat and potentially help save her brother Andy from a life-threatening immune disorder.

Rewind five years to when, after Andy was born in Mexico City, a barrage of infections kept him hospitalized for most of his first 16 months. When Andy’s doctors couldn’t understand why, they advised Andres and Paulina to find specialized care. Coincidentally, one of the Treviños’ neighbors had a cousin who worked at Children’s Hospital Boston. They learned the hospital is a a world leader in helping families overcome even the most complicated immune disorders. So they packed their bags and carried Andy thousands of miles away.

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Cord Blood in Action: The Pages Share Their Heartwarming Story

The Page Family SpeaksLike many expecting parents, Ben and Jamie Page debated the pros and cons associated with cord blood banking. After much discussion, they ultimately decided to save Harlow’s cord blood with ViaCord “just in case”. According to Jamie, “we did it not thinking we would need it just a few months later.” When Harlow was just four months old doctors discovered a “grapefruit sized mass in her stomach” and “nobody could agree” on what kind of cancer it was. As treatment options were discussed the Pages wondered if the stem cells from her cord blood could be used to treat their daughter’s aggressive cancer.

In an interview with MommyCast’s Gretchen Vogelzang, the Pages discuss this “heartwarming story with a great ending,” that reminds us what a valuable resource cord blood stem cells can be. As Gretchen says, “the best form of Continue reading

Are You a Survivor? June 5th Is National Cancer Survivors Day

National Cancer Survivors DayMillions of people have a story to tell—they have lived a fulfilling life after being diagnosed with cancer. National Cancer Survivors Day on June 5th is dedicated to giving these courageous survivors a voice to help inspire and give hope to others who may be facing the same challenges. National Cancer Survivors Day also celebrates the medical professionals who have helped advance the technologies we have to fight this complex disease. Where once there were no treatment options, there are now different ways to provide therapy—including cord blood stem cells transplants.

Celebrating progress
With the media’s focus usually on ongoing stem cell research, it’s easy to lose sight of the progress that has already been made. Nearly 80 diseases are currently treatable with cord blood stem cells, including certain types of cancers. To date, almost 40 of the 210 units ViaCord has released have gone to cancer treatments.

In fact, you may have seen a story in the news recently and on our blog about a little girl named Harlow who developed a grapefruit-sized tumor at just a few months old. Following treatment that included chemotherapy and surgery, Harlow’s own stem cells (banked with ViaCord) were used in a stem cell transplant to help prevent the tumor from growing back.  Harlow is now a happy and healthy 3 yr old that loves to dance, sing and watch her favorite movie, 101 Dalmations! National Cancer Survivors Day is the perfect time to celebrate this little survivor’s story and share her amazing tale.

Making a brother or sister into a hero
Siblings can also play an important role in a cancer treatment by donating their cord blood to a brother or sister in need. As in Harlow’s case, there are some types of childhood cancers that use the child’s own stem cells in treatment – an autologous transplant. However, many cord blood transplants are allogeneic, meaning the stem cells were donated.

The likelihood that a baby’s cord blood will be a match for siblings ranges from 25 to 75 percent, depending upon the acceptable match criteria determined by a doctor. One reason why transplants from family members are about twice as successful as those received from a non-related donor 2 is because of the lower possibility that the transplant will be rejected.Talk about becoming a sibling hero!  We featured a sibling hero story on our blog where Brayden’s cord blood was saved and used to help big brother Nick in his fight against Leukemia.

Knowing the importance of sibling cord blood was the reason ViaCord partnered with the Children’s Hospital Oakland Research Institute to create the Sibling Connection program. This program provides the ViaCord Complete Newborn Stem Cell Package™, which includes cord blood and cord tissue stem collection, processing and five years of storage at no cost to expecting parents who have a child in need of a transplant and meet the other enrollment requirements of the program. To learn more about the program click here.

Sharing stories of survival
From children to adults, sharing these stories of survival helps inspire others—what National Cancer Survivors Day is all about. There are events hosted in communities around the country where survivors and supporters can go to add their voice to the cause and provide hope to those diagnosed with cancer. To learn more about National Cancer Survivors Day or to get involved in one of these events, visit http://www.ncsdf.org. And be sure to share your stories in the comments at our Facebook® page or here on our blog.

Cord Blood in Action – Baby Harlow's Story

HarlowParental instinct is a powerful thing. Parents have an eye for ear infections and know the something-is-just-not-right signs of an impending cold or flu. For Jamie and her husband, Ben, they knew something was wrong when their daughter, Harlow, started crying more than usual just 2 weeks after she was born. Doctors said it was likely colic and suggested new formulas and different sleeping strategies, but Harlow wasn’t getting better. At 3 months old, her stomach swelled, and she stopped having wet diapers.

Putting a name to the problem

 After a trip to the emergency room and several tests, Jamie and Ben got some startling news: a grapefruit-sized, cancerous tumor was blocking Harlow’s kidney. To make matters worse, pathologists couldn’t identify just what type of cancer it was. Finally, a team of pediatric oncologists operating out of Chicago concluded that Harlow’s cancer most resembled a rare type of brain cancer, and should be treated as such.

Unsure of a prognosis for Harlow, doctors did determine chemotherapy was the best protocol for treatment. Although Jaime and Ben feared watching their daughter suffer the painful side effects, seeing her smile was enough to make them know they were not going to give up. Then they asked an important question: could the cord blood stem cells they banked with ViaCord help?

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Cord Blood Treatments Today – Thalassemia Major

Treating Thalassemia with Cord BloodWhen we think of cord blood, we often think of its potential to be used in medical treatments that are still being developed. And that potential is enormous. But it’s important to remember that cord blood already plays a critical role in treating—and in some cases curing—dozens of serious diseases and disorders.

One of these diseases is beta thalassemia major, also known as Cooley’s anemia. Beta thalassemia major is an inherited blood disorder that occurs when the genes governing the production of hemoglobin—the protein in red blood cells that binds to oxygen and carries it throughout the body—are flawed.

More specifically, hemoglobin contains two proteins, an alpha protein and a beta protein. In people afflicted with beta thalassemia major, the hemoglobin doesn’t contain enough of the beta protein, which means the red blood cells can’t carry sufficient oxygen from the lungs to the body’s cells and tissues.

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200 Units Released, 200 Families Given Hope

200 Units ReleasedViaCord has a long history of collecting and preserving babies’ stem cells. We’re proud to provide families with the opportunity to save the precious stem cells found in umbilical cord blood. The successful treatment of a number of conditions using cord blood stem cells proves they can be a valuable medical resource for families. Over the years ViaCord has seen many families in need of a stem cell treatment turn to the cord blood stem cells they’ve banked with us, especially where there may otherwise be limited treatment options.

Recently ViaCord released its 200th cord blood unit to be used for a potentially life-changing treatment.

Marking this newest milestone – 200 cord blood units released, 200 families given hope -is cause for acknowledgement and also provides an opportunity to reflect on the past and think about the future potential of cord blood stem cells.

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National Aplastic Anemia and MDS Awareness Week

AA and MDS Awareness WeekBone marrow failure disorders affect hundreds of thousands of people throughout the world, from children to adults. National Aplastic Anemia and MDS (myelodysplastic syndromes) Awareness Week (December 1-7) is helping to spread the word about two of these disorders. It is also an opportunity to shed light the role cord blood can play in helping to treating these potentially life-threatening diseases.

Why bone marrow matters
Bone marrow makes red and white blood cells and platelets that are vital to our existence. Each has a specific function—red blood cells carry oxygen and nutrients throughout the body; white blood cells help our bodies fight infection; and platelets help the blood clot and stop bleeding.

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Clinical Trials Offer Hope for Families Affected by Cerebral Palsy and Diabetes

Clinical TrialsToday, cord blood stem cells can be used to treat nearly 80 life-threatening diseases and are offering new hope to families affected by conditions that only years ago had no stem cell treatment options. A couple of the most exciting possibilities of cord blood stem cells lies in clinical trials now being conducted to determine whether a child’s own cord blood stem cells may be used to treat cerebral palsy and Type 1 Diabetes.

Cerebral Palsy
Cerebral palsy is a general term used to describe a group of neurological disorders that appear in early childhood and permanently affect muscle coordination and body movement. It is most often caused by brain injury or Continue reading

Finding a Match – Knowing the Difference between Related and Non-related Stem Cells

socks3_iStock_000007718811XSmallStem cells have been used in transplant medicine with much success for the last 40 years. Since 1988, stem cells from umbilical cord blood have played a critical role in that success. Growing numbers of expectant parents are donating children’s cord blood or enrolling in family banking, based on the profound potential in cord blood stem cells.

In the event those stem cells are needed for allogeneic transplant, a successful outcome is largely dependent on finding a compatible match from a donor who can be related, like a sibling, or of no relation at all. When a patient is in need the determination of who the donor will be is based on tissue matching. Understanding the basics of tissue matching is key to making an informed decision about what to do with your baby’s cord blood.

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Cord Blood Treatments – Autologous Transplants & Infusions

AutologousIn a recent blog post, we discussed allogeneic transplants  and how they can be used to help treat a number of diseases. But did you know that autologous treatments, using a child’s own cord blood, can also help treat some of those same diseases, and are also on the forefront of a new and exciting area of research?

There are multiple applications for autologous treatments:

*  In an autologous transplant a child’s own cord blood stem cells are transplanted back into that child to help treat some cancers, such as neuroblastoma and brain cancer. Autologous transplants require a pre-transplant conditioning regimen like alleogeneic transplants. They can also be used to treat acquired blood disorders, as opposed to blood disorders that are genetic. For example, complications from an organ transplant may result in acquired aplastic anemia. The child’s own cord blood could then be used to treat the acquired condition.

*  In an autologous re-infusion a child’s own cord blood stem cells are re-infused into that child to help repair and re-grow cells that may be damaged. This emerging field of medicine is directed at treatments for conditions which have no cure today, such as Cerebral Palsy and Type 1 Diabetes. Re-infusions do not require a conditioning regimen like transplants do.

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